Profile
- Name : Dr. Anupam Mukherjee
- Designation : Scientist D
- Division : Molecular Virology
- Email ID : [email protected]; [email protected]
- Area Of Interest : Dr. Mukherjee has a long-term goal to develop RNAi, i.e. miRNA or siRNA as potential therapeutics against HCV, HIV and HIV-associated other opportunistic viral infections. From initiation to 10 years’ down-the-lane, Dr. Mukherjee and his team would like to continue their research in the field of RNAi. After identification and characterization of these molecules, their susceptibility to the specific viruses will be checked, targated delivery system through tagging with nano-particles and post-delivery outcomes will be examined. Therefore, his research interests will elucidate additional therapeutic modalities and will deliver the laboratory to bedside pills for eradication of most deleterious viruses.
- Completed and Ongoing Projects
- Awards and Honours
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- RAMANUJAN Fellow of SERB – Department of Science & Technology
- Member of Indian Science Congress Association
- Member of European Society for Clinical Virology
- Member of International Society for Infectious Diseases
- Award – 13th International dsRNA Virus Symposium, Houffalize, Belgium in 2018
- ICMR-Research Associate – ICMR, New Delhi in 2016
- Young Scientist – SERB-DST, New Delhi in 2015
- DS Kothari Fellow – UGC-DSKPDF Cell, Pune in 2015
- ICMR-PDF fellowship – ICMR, New Delhi in 2011
- Junior Scientist Award – 14th ICID, Miami, USA, by DST, New Delhi in 2010
- Award – 4th Euroepan Congress of Virology, Como, Italy, by ESCV, in 2010
- ICMR-SRF fellowship – ICMR, New Delhi in 2009
- Editorial Board Member: MEEGID – Infection Genetics Evolution, Elsevier
- Associate Editor: Viruses – MDPI Open Access
- Official Referee: Frontiers in Cell and Developmental Biology (Frontiers)
- Official Referee: PLOS One (PLOS)
- Official Referee: Biological Research (BMC Springer Nature)
- Official Referee: Cancer Biomarkers (Hindawi)
- Official Referee: Virus Research (Elsevier)
- Official Referee: Archives of Medical Science (Termedia)
- Official Referee: Cancer Investigation (Taylor & Francis Group)
- Work Experience
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- Scientist D & In-Charge, Division of Virology, ICMR-National AIDS Research Institute, Pune, India. 2019 – Ongoing
- RAMANUJAN Fellow Scientist at ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India. 2016-2019
- DST Young Scientist at ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India. 2015-2016
- Research Scientist at ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India. 2015
- Postdoctoral Research Associate at Saint Louis University, Department of Pathology, Missouri, 2013-2015
- Postdoctoral Research Fellow at ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India. 2011-2013
- Senior Research Fellow at ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India. 2009-2011
- List of Grant Recieved
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- Investigation of the Efficiency of microRNA (miRNA) Loaded Nanoparticles in the Inflammasome-Mediated Extenuation of HSV-2 Pathogenesis
DHR-HRD: 2021-2024; PI/Mentor
- Exploration of Ayurveda-based Rasayana Botanicals for Biological Synthesis of Nanoparticles and its Application as HIV-1 Inhibitors Through in vitro Studies
DHR-HRD: 2021-2024; PI/Mentor
- Study of regulation of RNA interference during rotavirus infection
DST-SERB: 2017-2020; Co-PI
- MicroRNAs and Exosomes: The Key Players in Rotavirus Infection
DST-SERB: 2016-2021; PI
- National Program: Apex Laboratory for HIV-1 Viral Load testing and VLPT Program
NACO-MSACS: 2021-ongoing; In-charge
- Significance of Retinoic Acid Inducible Gene-I-Like Receptors (RLRs) and Toll-like Receptors (TLRs) In the Induction of Anti-Rotaviral Innate Immunity
ICMR-PDF: 2011-2013; PI
- Genomic Characterization of Human Rotavirus Strains Circulating in Manipur, India
ICMR-SRF: 2009-2011; PI
- Conference/Training/Workshop Attended
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- ESCV Virtual Meeting on Covid 19, Madrid, Spain IN 2020.
- 14th Vaccine Congress–online edition: Combatting the threat of COVID-19, Vaccine, Elsevier, 2020.
- Induction Program for ICMR Scientists at ICMR-NIRRH, Mumbai in 2019.
- 6th Molecular Virology Meeting at IIT Kharagpur, India in 2019.
- 13th International dsRNA Virus Symposium, Houffalize, Belgium in 2018.
- Keystone Symposia: Cells vs. Pathogens: Intrinsic Defenses and Counter Defenses, Monterey, California, USA in 2018.
- 21st International Symposium on Hepatitis C Virus and Related Viruses, Banff, Canada in 2013.
- 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, California, USA in 2014.
- 4th Euroepan Congress of Virology, Villa Erba Cernobbio, Como, Italy in 2010.
- 14th International Congress on Infectious Diseases, Miami, USA in 2010.
- The 97th Indian Science Congress: Medical Sciences, Indian Space Research Organization, Thiruvanantapuram, India in 2010.
- S. - Japan CMSP: 13th International Conference on Emerging Infectious Diseases (EID) in The Pacific Rim – Focused on Enteric Diseases, in 2009.
- Number of Publications : 29
- List of Publications
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2021
Mukhopadhyay U, Banerjee A, Chawla-Sarkar M and Mukherjee A. Rotavirus Induces Epithelial–
Mesenchymal Transition Markers by Transcriptional Suppression of miRNA-29b. Front.
Microbiol. 2021; 12:631183. doi: 10.3389/fmicb.2021.631183. [Impact factor – 5.640; Citation -0]
Klionsky DJ, et al. Among authors: Mukherjee A. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021; 1-382. doi: 10.1080/15548627.2020.1797280. Epub ahead of print. PMID: 33634751. [Impact factor – 16.016; Citation -7509]
2020
Banerjee A, Kulkarni S, Mukherjee A. Herpes Simplex Virus: The Hostile Guest That Takes Over Your Home. Front Microbiol, 2020; 11:733. [Impact factor – 5.640; Citation -8]
Saha P, Biswas M, Gupta R, Majumdar A, Mitra S, Banerjee A, Mukherjee A, Dutta S, Chawla-Sarkar M. Molecular characterization of Influenza A pandemic H1N1 viruses circulating in eastern India during 2017-19: Antigenic diversity in comparison to the vaccine strains. Infect Genet Evol, 2020; 81:104270. [Impact factor – 3.342; Citation -3]
2019
Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Komoto S, Chawla-Sarkar M. Bi-phasic regulation of RNA interference during Rotavirus infection by modulation of Argonaute2. Cellular Microbiology, 2019; 21(12):e13101. [Impact factor – 4.288; Citation -3]
Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Rana S, Mukherjee A#, Chawla-Sarkar M. Synchronized Orchestration of miR-99b and let-7g Positively Regulates Rotavirus Infection by Modulating Autophagy. Scientific Reports, 2019; 9(1):1318. [Impact factor – 4.379; Citation -11]
#Co-corresponding author
2017
Doan YH, Suzuki Y, Fujii Y, Haga K, Fujimoto A, Takai-Todaka R, Someya Y, Nayak MK, Mukherjee A, Imamura D, Shinoda S, Chawla-Sarkar M, Katayama K. Complex reassortment events of unusual G9P[4] rotavirus strains in India between 2011 and 2013. Infect Genet Evol, 2017; 54:417-428. [Impact factor – 3.342; Citation - 18]
2016
Mukherjee A, Nayak MK, Dutta S, Panda S, Satpati BR, Chawla-Sarkar M. Genetic Characterization of Circulating 2015 A(H1N1) pdm09 Influenza Viruses from Eastern India. PLoS ONE, 2016; 11(12):e0168464. [Impact factor – 3.240; Citation - 16]
Mandal P, Mullick S, Nayak MK, Mukherjee A, Ganguly N, Niyogi P, Panda S, Chawla-Sarkar M. Complete genotyping of unusual species A rotavirus G12P[11] and G10P[14] isolates and evidence of frequent in vivo reassortment among the rotaviruses detected in children with diarrhea in Kolkata, India, during 2014. Arch Virol, 2016; 161(10):2773–2785. [Impact factor – 2.574; Citation - 14]
2015
Mukherjee A, Di Bisceglie AM, Ray RB. Hepatitis C Virus Mediated Enhancement of miR-373 Impairs JAK/STAT Signaling Pathway. J Virol, 2015; 89(6):3356-65. [Impact factor – 5.103; Citation - 69]
2014
Mullick S, Mukherjee A, Ghosh S, Pazhani GP, Sur D, Manna B, Nataro JP, Levine MM, Ramamurthy T, Chawla-Sarkar M. Community Based Case-Control Study of Rotavirus Gastroenteritis among Young Children during 2008-2010 Reveals Vast Genetic Diversity and Increased Prevalence of G9 Strains in Kolkata. PloS ONE, 2014; 9(11): e112970. [Impact factor – 3.240; Citation - 18]
Mukherjee A, Shrivastava S, Ray R, Ray RB. Transcriptional Suppression of miR-181c by Hepatitis C Virus Enhances Homeobox A1 Expression. J Virol, 2014; 88(14):7929-40. [Impact factor – 5.103; Citation - 50]
Ray RB, Mukherjee A, Shrivastava S, Ray R. Hepatitis C virus transcriptionally downregulates miR-181c for promotion of hepatocyte growth towards hepatocellular carcinoma. Cancer Research, 2014; 74(19): 3177-3177. [Impact factor – 12.701; Citation - 1]
2013
Shrivastava S, Mukherjee A*, Ray R, Ray RB. Hepatitis C Virus Induces IL-1β/IL-18 in Circulatory and Resident Liver Macrophages. J Virol, 2013; 87(22):12284-90. [Impact factor – 5.103; Citation - 115] *Co-first author
Shrivastava S, Mukherjee A*, Ray RB. Hepatitis C virus infection, microRNA and liver disease progression. World J Hepatol, 2013; 5(9): 479-86. [Impact factor – 2.730; Citation - 79]
*Co-first author
Kang G, Desai R, Arora R, Chitamabar S, Naik TN, Krishnan T, Deshpande J, Gupte MD, S Venkatasubramaniam, Gentsch JR, Parashar UD, Mathew A, Anita S, Ramani S, Sowmynarayanan TV, Moses PD, Agarwal I, Simon A, Bose A, Arora R, Chhabra P, Fadnis P, Bhatt J, Shetty SJ, Saxena VK, Mathur M, Jadhav A, Roy S, Mukherjee A, Singh NB. Diversity of circulating rotavirus strains in children hospitalized with diarrhea in India, 2005-2009. Vaccine, 2013; 31(27):2879-2883. [Impact factor – 4.422; Citation - 96]
Roy Mukherjee T, Mukherjee A, Chawla-Sarkar M. Full genomic analysis of human group C Influenza from eastern India. Infect Genet Evol, 2013; 16:419-25. [Impact factor – 3.342; Citation - 14]
Chattopadhyay S, Basak T, Nayak MK, Bhardwaj G, Mukherjee A, Bhowmick R, Sengupta S, Chakrabarty O, Chatterjee NS, Chawla-Sarkar M. Identification of cellular calcium binding protein calmodulin as a regulator of rotavirus A infection during comparative proteomic study. PLoS ONE, 2013; 8(2): e56655. [Impact factor – 3.534; Citation - 29]
2012
Mukherjee A, Mullick S, Deb AK, Panda S, Chawla-Sarkar M. First Report of Human Rotavirus G8P[4] Gastroenteritis in India: Evidence of Ruminants-to-Human Zoonotic Transmission. J Med Virol, 2012; 85:537–545. [Impact factor - 2.373; Citation - 30]
Mullick S, Mukherjee A, Ghosh S, Pazhani GP, Sur D, Manna B, Nataro JP, Levine MM, Ramamurthy T, Chawla-Sarkar M. Genomic analysis of human rotavirus strains G6P[14] & G11P[25] isolated from Kolkata in 2009 reveals interspecies transmission and complex reassortment events. Infect Genet Evol, 2012; 14(1):15-21. [Impact factor – 3.730; Citation - 42]
Mukherjee A, Mullick S, Kobayashi N and Chawla-Sarkar M. The First Identification of Rare Human Group A Rotavirus Strain G3P[10] with Severe Infantile Diarrhea in Eastern India. Infect Genet Evol, 2012; 12(8):1933-7. [Impact factor – 3.730; Citation - 20]
Mukherjee A, Chatopadhyay S and Chawla-Sarkar M. Rotavirus Infection in India: a major cause of childhood gastroenteritis. Review, Proceedings of the National Academy of Science, India, 2012; 82(1):135–51. [Impact factor – 1.544; Citation - 1]
Mukherjee A, Nayak MK, Roy T, Ghosh S, Naik TN, Kobayashi N, Chawla-Sarkar M. Detection of G10 Rotavirus Strains from Untypable Samples: Evidence for Interspecies Recombination in Human Group A Rotavirus Strains. Infect Genet Evol, 2012; 12(2):467-70. [Impact factor – 3.730; Citation - 30]
2011
Dutta D, Chattopadhyay S, Bagchi P, Halder UC, Nandi S, Mukherjee A, Kobayashi N, Taniguchi K, Chawla-Sarkar M. Active participation of cellular chaperone Hsp90 in regulating the function of rotavirus nonstructural protein 3 (NSP3). J Biol Chem, 2011; 3; 286(22):20065-77. [Impact factor – 5.157; Citation - 35]
Mukherjee A and Chawla-Sarkar M. Rotavirus Infection: A Perspective on Epidemiology, Genomic Diversity and Vaccine Strategies. Review, Indian J Virol/VirusDiseases, 2011; 22(1):11–23. [Impact factor – 0.364; Citation - 16]
Roy T, Agrawal AS, Mukherjee A, Mishra AC, Chadha MS, Kaur H, Chawla-Sarkar M. Surveillance and Molecular characterization of human influenza B viruses during 2006-2010 revealed co-circulation of Yamagata-like and Victoria-like strains in eastern India. Infect Genet Evol, 2011; 11(7):1595-601. [Impact factor – 3.128; Citation - 34]
Mukherjee A, Ghosh S, Bagchi P, Dutta D, Chattopadhyay S, Kobayashi N, Chawla-Sarkar M. Full genomic analyses of human G4P[4], G4P[6], G9P[19] and G10P[6] strains from North-eastern India: Evidence for interspecies transmission and complex reassortment events. Clin Microbiol Infect, 2011; 17(9): 1343–6. [Impact factor – 8.067; Citation - 66]
2010
Mukherjee A, Roy T, Agrawal AS, Sarkar M, Lal R, Chakrabarti S, Chawla-Sarkar M. Prevalence and epidemiology of pandemic H1N1 strains in hospitals of Eastern India. J Pub Health Epidemiol, 2010; 2(7): 171-4. [Impact factor – not received yet; Citation - 50]
Chattopadhyay S, Bagchi P, Dutta D, Mukherjee A, Kobayashi N, Chawla-Sarkar M. Computational identification of the post-translational modification sites and the functional family prediction reveals possible moonlighting role of rotaviral proteins. Bioinformation, 2010; 4(10): 448-51. [Impact factor – 0.60; Citation - 13]
Bagchi P, Dutta D, Chattopadhyay S, Mukherjee A, Halder UC, Sarkar S, Kobayashi N, Komoto S, Taniguchi K, Chawla-Sarkar M. Rotavirus Non-Structural Protein-1 suppresses virus induced cellular apoptosis to facilitate viral growth by activating the cell-survival pathways during early stages of infection. J Virol, 2010; 84(13):6834-45. [Impact factor – 5.189; Citation - 89]
Mukherjee A, Chattopadhyay S, Bagchi P, Dutta D, Singh NB, Arora R, Parashar UD, Gentsch JR, Chawla-Sarkar M. Surveillance and molecular characterization of rotavirus strains circulating in Manipur, north-eastern India: Increasing prevalence of emerging G12 Strains. Infect Genet Evol, 2010; 10(2):311-20. [Impact factor – 3.086; Citation - 75]
2009
Kang G, Arora R, Chitambar SD, Deshpande J, Gupte MD, Kulkarni M, Naik TN, Mukherji D, Venkatasubramaniam S, Gentsch JR, Glass RI, Parashar UD, Mathew A, Gonsalez A, Ramani S, Sowmynarayanan TV, Moses PD, Agarwal I, Simon A, Bose A, Arora R, Chhabra P, Fadnis P, Bhatt J, Shetty SJ, Saxena VK, Mathur M, Jadhav A, Roy S, Mukherjee A, Singh NB. Multicenter, hospital-based surveillance of rotavirus disease and strains among indian children aged <5 years. J Infect Dis. 2009; 200 Suppl 1:S147-53. [Impact factor – 6.288; Citation - 155]
Dutta D, Bagchi P, Chatterjee A, Nayak M K, Mukherjee A, Chattopadhyay S, Nagashima S, Kobayashi N, Satoshi K, Taniguchi K, Chawla-Sarkar M. The Molecular Chaperone Heat Shock Protein-90 Positively Regulates Rotavirus Infection. Virology, 2009; 391(2):325-33. [Impact factor – 3.616; Citation - 56]
Mukherjee A, Dutta D, Ghosh S, Bagchi P, Chattopadhyay S, Nagashima S, Kobayashi N, Dutta P, Krishnan T, Naik TN, Chawla-Sarkar M. Full genomic analysis of a human group A rotavirus G9P[6] strain from Eastern India provides evidence for porcine to human interspecies transmission. Arch Virol, 2009; 154(5):733-46. [Impact factor – 2.574; Citation - 58]
