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Dr. HariOm Singh
Name : Dr. HariOm Singh
Designation : Scientist D
Division : Molecular Biology
Email ID : [email protected]/[email protected]
Area Of Interest : Host Genetics, Pharmacogenomics
Awards and Honours
  • NIH Office of AIDS Research (OAR) Training Fellowship Award, 2018
  • Young Scientist Award- ICIPMBS-2018
Work Experience

Work Experience

Post Held








Research & Development

 Scientist D


September 2019

Till date

Research & Development

NIH Fellow

State University of New York, USA

April 2019

August 2019

 Research & Development

 Scientist C



 September 2015

March 2019

Research & Development

Scientist B



August 2010

September 2015

Research & Development

ICMR-Research Associate


Feb 2010

July 2010


List of Grant Recieved

List of grants received


Title of Project


Funding Agency



 Comparative analysis of genetic variation and expression of Apo family of lipoprotein, lipid metabolizing enzyme and transporter genes between HIV-associated lipodystrophy patients taking PIs with and without the history of receiving stavudine or zidovudine based regimen



Rs 5300000



Comparative analysis of Host factors among individuals with novel Coronavirus infection



Rs 7397918



Study of genetic variation and expression of drug metabolizing enzyme, transporter and Apolipoprotein genes between TDF and TAF -related renal dysfunction among patients of HIV - hepatitis B co-infection

36 month

Approval awaiting



Conference/Training/Workshop Attended

Conferences/Trainings/Workshops Attended

  • 1) Revolutionize cell line development & Engineering to improve product quality, reduce time lines & increase titers at Park  central Hotel, San Francisco, CA, June 18-20,2019

    2) Structure Biology Related to HIV/AIDS at NIH on June 27-28, 2019 at Natcher conference center Bethesda, Maryland, US

    3) Meeting on Microbiome at Cold Spring Harbor Laboratory, New York, July 18-21,2019


Number of Publications : 36
List of Publications

List of Publications

  1. Singh H, Krishnaraj A, Lata S, Dhole TN. Genetic variation of matrix metalloproteinase enzyme in HIV-associated neurocognitive disorder. 2019 May 25; 698:41-49. 
  2. Singh H, Lata S, Choudhari R, Dhole T.N. Prevalence of ABCC3 1767G/A polymorphism among patients with antiretroviral -associated hepatotoxicity. Molecular Genetics & Genomic Medicine. (Accepted on 26 November 2019)
  3. HariOm Singh, Sushma Jadhav, Dharmesh Samani. Tissue Inhibitor of Metalloproteinase-2 polymorphisms and Risk for HIV-associated neurocognitive disorder. Mediators of Inflammation 2019, May 28,10 pages, 2019.
  4. Singh HO, Maan HS, Dhole TN. Gene Silencing: A Novel Approach and Suppression of HIV-1 Gene. J Mol Genet Med 2019 April 22: 13: 420
  5. Singh HLata SDhole TNGangakhedkar RR. Occurrence of CYP2B6 516G>T polymorphism in patients with ARV-associated hepatotoxicity. Mol Genet Genomic2019 Apr;7(4):e00598
  6. Hari Om Singh, Sushma Jadhav, Dharmesh Samani, T.N Dhole. Polymorphisms in miRNAs gene (146a, 149, 196a) and susceptibility to ARV-associated hepatotoxicity. Current Genomics, 2019 Feb;20(2):134-150.
  7. HariOm Singh, Dharmesh Samani, R.Gangakhedkar. Interleukin-10 polymorphisms and Susceptibility to ARV associated hepatotoxicity. Microbial Pathogenesis 2019 May 20; 133:103544.
  8. Singh H, Nambiar N, Samani D, Gangakhedkar RR. Occurrence of Interleukin-2 (330 G/T) Promoter Polymorphism in ARV associated hepatotoxicity. Curr Mol Med. 2019 Apr 10. doi: 10.2174/1566524019666190411093451.
  9. Singh H, Gangakhedkar RR. Occurrence of APOBEC3G variations in West Indian HIV patients. Microb Pathog. 2018 Jun 2; 121:325-330.
  10. Singh H, Lata S, Gangakhedkar RR. Prevalence of CYP2D6*4 1934G/A Polymorphism in Western Indian HIV patients. 2018 Nov;126(11):842-851
  11. Singh H, Samani D, Nema V, Ghate M.V, and Gangakhedkar R,R. IL-1RN and IL-1β Polymorphism and ARV-Associated Hepatotoxicity. Mediators of Inflammation. 2018 Apr 8;2018:4398150
  12. Singh H, Samani D, Nambiar N, Ghate MV, Gangakhedkar RR. Effect of matrix metalloproteinase-21 (572C/T) polymorphism on HIV-associated neurocognitive disorder. 2018 Apr;126(4):329-336.
  13. Singh H, Samani D, Nambiar N, Ghate MV, Gangakhedkar RR.Prevalence of MMP-8 gene polymorphisms in HIV-infected individuals and its association with HIV-associated neurocognitive disorder. 2018 Mar 10;646:83-90
  14. Singh H. Matrix Metalloproteinases Enzyme and Risk for HIV-Associated Neurocognitive Disorders. Austin Journal of HIV/AIDS Research.  January 30, 2018
  15. Singh H, Samani D, Ghate MV, Gangakhedkar RR. Impact of cellular restriction gene (TRIM5α, BST-2) polymorphisms on the acquisition of HIV-1 and disease progression. J Gene Med. 2018 Feb; 20(2-3):e3004.
  16. Singh H, Lata S, Nema V, Samani D, Ghate M, Gangakhedkar CYP1A1m1 and CYP2C9*2 and *3 polymorphism and risk to develop ARV-associated hepatotoxicity and its severity. APMIS. 2017 Jun; 125(6):523-535.
  17. Singh H, Samani D, Ghate MV, Gangakhedkar R,R. Impact of cellular restriction gene (TRIM5α, BST-2) polymorphisms on the acquisition of HIV-1 and disease progression. J Gene Med. 2017 Dec 28. doi: 10.1002/jgm.3004
  18. Singh H, Marathe S D, Samani D, Nema V, Ghate M V, Gangakhedkar R . Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND. J Biosci. 2017 September, 42, 481–490
  19. Singh HO, Lata S, Angadi M, Bapat S, Pawar J, Nema V, Ghate MV, Sahay S, Gangakhedkar Impact of GSTM1, GSTT1 and GSTP1 gene polymorphism and risk of ARV-associated hepatotoxicity in HIV-infected individuals and its modulation. Pharmacogenomics J. 2017 Jan; 17(1):53-60.
  20. Vijay Nema, Hari Om Singh. Host Pharmacogenomics: to be Remembered while Planning a Cure for HIV. BAOJ Hiv 2017 3:1
  21. Singh H, Marathe S, D, Nema V, Ghate M. V, Gangakhedkar R, R. Impact of variants of MMP-7(-181A>G) gene in susceptibility to development of HAND and its severity. 2016 Nov;124(11):966-972
  22. HariOm Singh, Shruti D Marathe, Vijay Nema, Manisha Ghate, Raman R.Gangakhedkar. Genetic variation of MMP-2 & MMP-9 polymorphism in susceptibility to development of HAND and its severity. J Gene Med. 2016 Sep;18(9):250-7.
  23. HariOm Singh, Shruti D Marathe, Vijay Nema, Manisha V Ghate, Raman.R.Gangakhedkar. APOBEC3B deletion impacts on susceptibility to acquire HIV-1 and its advancement among Individuals in Western India. APMIS. 2016 Oct;124(10):881-7
  24. HariOm Singh, Shruti Marathe, Mansa Angadi, Shradha Bapat, Jyoti Pawar,Vijay Nema, Manisha Ghate, Seema Sahay, R.R.Gangakhedkar .Coding region variant 186H/R in Exon 4 of APOBEC3G among individuals of Western India. APMIS. 2016 May;124(5):401-5
  25. Supriya D. Mahajan*,Asmita Gaekwad, Jyoti Pawar, Srikanth Tripathy, Manisha Ghate, Jayanta Bhattacharya, HariOm Singh, Stanley A. Schwartz, Ramesh Paranjape and Raman  Cardiac Morbidity in an HIV-1 Lipodystrophy Patient Cohort Expressing the TNF-α-238 G/A Single Nucleotide Gene Polymorphism. Curr HIV Res. 2015; 13(2):98-108.
  26. Anu Sharma, Hariom Singh, Sarvesh Paliwal. Recent Advances in use of Semicarbazones as Anticonvulsant Agents: A Review.   Biomed. Ther. Sci. 2015, 2(1), 1-7
  27. Hari Om Singh, Amita Singh, TN Dhole. Effect of Ormeloxifene for Management of Dysfunctional Uterine Bleeding. Biochem Physiol 2015, 4:3
  28. Hari Om Singh, Amita Singh, TN Dhole. Factor associated to Bacterial Vaginosis in Nonpregnant women of North Indian population. J Biotechnol Biomater 2015, 5:3
  29. Hari OS, Sonali G. Awareness and Trends of Blood Cholesterol and Susceptibility to Develop Heart Disease. Adv Genet Eng 2015, 4:3
  30. Gangwar R, Mittal B. Srivastava Shuti, Singh H, Mittal R Genetic Variants of DNA Repair Gene XPC Modulating Susceptibility to Cervical Cancer in North India. Onco Res 2010; 18:1-100
  31. Singh H, Jain M, Mittal B. TGF-β1 (-509C/T) Gene Polymorphisms and Susceptibility to Cervical Cancer.Onco Res. 2009; 18(1):41-5.
  32. Singh H, Sachan R, Devi S, Pandey S N, Mittal Association of GSTM1, GSTT1 and GSTM3  gene polymorphisms and susceptibility to cervical cancer in North Indian population. Am J Obstet Gynecol. 2008; 198:303-6.
  33. Singh H, Sachan R, Geol H, Mittal Genetic Variations in Interleukin-1 receptor antagonist and Interleukin-1β genes and cervical cancer. British J. Obstetrics and Gynecology 2008; 115:633–638.
  34. Singh H, Sachan R, Jain M, Mittal B. CCR5-∆32 Polymorphism and Susceptibility to Cervical Cancer: Association with Early Stage of Cervical Cancer. Oncol Res. 2008; 17:87-91.
  35. Singh H, Jain M, Sachan R, Mittal TNF-α (-308G/A) and IL-10(-819C/T) Promoter Polymorphisms and Risk of Cervical Cancer. Int. J Gynecological Cancer 2009; 19(7):1190-1194.
  36. Singh H, Jain M, Mittal B. MMP-7(-181 A/G) Gene Polymorphisms and Risk for Cervical Cancer. Gynecol Oncol. 2008; 110:71-5.

Book chapter

  1. Sumitra Nain, Garima Mathur,Pragati Karana, and HariOm Singh. Physical and Chemical Properties of Nanobiomaterials. Pharmaceutical Technology (Nanobiomaterials
    Applications in Drug Delivery) Apple Academic Press. Mar, 2017

Gene sequence

  1. Jagtap,D.D., Gupte,D.S., Thakar,M.R., Singh,H.O., Pandey,S., C,S.K. and Paranjape,R.S. Molecular characterization of tetherin/BST-2 gene promoter in  Indian HIV infected long term non progressors. GenBank-2014