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Dr. Abdul Arif Khan
Name : Dr. Abdul Arif Khan
Designation : Scientist D
Division : Microbiology
DOB : 26-12-1979
Email ID : akhan@nariindia.org, khan.aa@icmr.gov.in
Area Of Interest : Host-Pathogen interactions, System Biology, Cancer associated infections, Candida infection
Awards and Honours
  • Artificial Intelligence Molecular Screen Award (AIMS) from Atomwise Inc. USA (2019)
  • Awarded Ramanujan Fellowship by the Science and Engineering Research Board (SERB), Department of Science and Technology, Government of India (Year 2019).
  • Received "Certificate for Outstanding Research Achievement" through Deanship of Scientific Research, King Saud University, Riyadh KSA (Year 2019)
  • Received “The 2017 Albert Nelson Marquis Lifetime Achievement Award” through Marquis Who’s Who, USA
  • Received Top 100 Scientists-2013 award by International Biographical Centre, Cambridge, England
  • Received Young Scientist Meeting Grant Award from Federation of European Microbiological Societies (FEMS), Netherlands, for year 2007
  • Received Young Scientist Award for Best Presentation in MP Science Congress, Indian Science Congress Association, Bhopal Chapter for the year 2004 (Sponsored by Asian Journal of experimental sciences)
  • Selected in Graduate Aptitude Test in Engineering (GATE) 2005 examination with 95.62 percentile (All India Rank 286)
  • Selected in Graduate Aptitude Test in Engineering (GATE) 2004 examination with 84.33 percentile (All India Rank 753)
  • Secured position among top three students in the merit of Jiwaji University MSc (Applied Microbiology) 2002 examination
Work Experience

Work Experience

Post Held

Employer

Duration

Scientist D

National AIDS Research Institute, Pune, India

15 Nov 2019 - Present

Associate Professor

College of Pharmacy, King Saud University, KSA

12 Jun 2017- 23 Aug 2019

Assistant Professor

College of Pharmacy, King Saud University, KSA

10 Jan 2010-11 Jun 2017

Faculty Associate

School of Biotechnology, Gautam Buddha University, Greater Noida, India

06 Apr 2009-01 Jan 2010

Assistant Professor

College of Life Sciences, Cancer Hospital & Research Institute, Gwalior, India

02 Mar 2005-04 Apr 2009

Teaching Faculty

Government Autonomous Kamla Raja Girls College, Gwalior, India

01 Jan 2003–28 Feb 2005

 

List of Grant Recieved

List of grants received

Sr.No.

Title of Project

Duration

Funding Agency

Role

1

Artificial intelligence based one molecule development for simultaneous management of cancer and associated Candida infection.

2020-2022

Atomwise Inc. USA

PI

2

Amelioration of dental caries: evaluation of indigenous plant products

2006-08

University Grants Commission, New Delhi

PI

3

Travel grant from, for participation in “International conference on Bioinformatics and Comparative genome analysis” held at Institute of Pasteur, Tunisia from 18-03-2007 to 07-04-2007

2007

Department of Science and Technology (DST), Govt. of India

Awardee

4

Received FEMS young scientist meeting grant for participation in International conference on “Campylobacter Helicobacter and related organism 2007 (CHRO 2007)” at Rotterdam, Netherlands

 

2007

Federation of European Microbiological Societies, Netherlands

Awardee

 

Conference/Training/Workshop Attended

Conferences/Trainings/Workshops Attended

  • Selected (Among 20 candidates globally and only two from Asia) for the participation in International course on Bioinformatics and comparative genome analysis organized by Institute of Pasteur Paris, European Molecular biology organization (UK), CNRS (France), Institute of Pasteur Tunis from 18-03-2007 to 07-04-2007
  • Participated International conference on “Bioinformatics and comparative genome analysis” organized by Institute of Pasteur, Paris, EMBO, and Institute of Pasteur, Tunis at Tunisia from 2nd April to 7th April 2007
  • Participated International conference on Toxicology, Toxicogenomics and Occupational Health held during 9-11 Oct. 2006 at Jiwaji University, Gwalior and presented a poster titled “Isolation and analysis of Ochratoxin isolated from Aspergillus ochraceus isolated from dry fruits
  • Participated in National conference on Food 2020 at Centre for food Technology Jiwaji University Gwalior and presented a poster titled “Food as a vaccine
  • Participated M. P. Sciences Congress- 2004 (Indian Science Congress Association, Bhopal chapter) and presented a paper titled “Effect of leaf extracts on the growth of E. coli”
  • Participated in National symposium on Immunomodulation in health and disease held during 14-15 Dec. 2001 at G.B. Pant University, Pantnagar, INDIA
  • Participated UGC- DSA National conference on “Bio resource: Utilization and Conservation” held during 17-18 Feb 2006 at Saurashtra University, Rajkot, Gujarat, INDIA
  • Participated symposium on “How to write Scientific/Medical paper” held on 24th 2006 at Cancer Hospital & Research Institute, Gwalior, INDIA
  • Participated 47th Association of Microbiologist of India conference at Barkatullah University, Bhopal from 6th to 8th December 2006 and presented a poster titled “Bacterial infections jeopardizing patients to cancer”
  • Participated workshop-2008 titled “Nanotechnology of protein estimation” organized by Gajra Raja Medical College, Gwalior (MP) India on 9th Feb 2008
  • Participated symposia on “Biotech 2005: Challenges and opportunities” organized by GICTS college, Gwalior on 19th April 2005
  • Participated in national seminar on “Nanotech – 2008” organized by College of Life Sciences, Cancer Hospital & Research Institute, Gwalior (MP) on 28th Feb 2008
  • Participated in national seminar on “Recent advances in environmental sciences” organized by P.G. department of Life Sciences, Institute of Allied Sciences and computer application, ITM Universe, Gwalior (MP) on 27th- 28th Feb 2009
Number of Publications : 49
List of Publications

List of Publications

Books (International)
  1. Abdul Arif Khan (Ed.) Bacteria and Cancer, Springer Science Publisher, Netherlands (2012) (ISBN 978-94-007-2584-3)
  2. Sudhir Kumar Jain, Abdul Arif Khan and M.K.Rai (Ed.) Geomicrobiology, Science Publisher, Taylors and Francis, CRC Press, USA (2010) (ISBN 978-1-57808-665-8)

Research Papers and Reviews (All Impact factors are at the time of publication)

First and/or corresponding author

  1. Khan A.A.*, Khan Z., Malik A., Kalam M.A., Cash P. Alshamsan A. (2017) Colorectal cancer-inflammatory bowel disease nexus and felony of Escherichia coli. Life Sci (doi: https://doi.org/10.1016/j.lfs.2017.05.016) (Impact factor: 2.685)
  2. Khan A.A.*, Khan Z., Kalam M.A., Khan A.A. (2016) Inter-kingdom prediction certainty evaluation of protein subcellular localization tools: microbial pathogenesis approach for deciphering host microbe interaction. Briefings in Bioinformatics (doi: 10.1093/bib/bbw093) (Impact factor 8.399) (First & Corresponding author)
  3. Khan A.A.*, Khan Z., Warnakulasuriya S. (2016) Cancer associated toll like receptor modulation and insinuation in infection susceptibility: association or coincidence? Ann Oncol (doi: 10.1093/annonc/mdw053) (Impact factor 9.269) (First & Corresponding author).
  4. Shrivastava A., *Khan A.A., Khurshid M., Kalam M., Jain S.K., Singhal P.K. (2016) Recent developments in the field of L-asparaginase discovery: a potential anticancer agent Equal Contribution] Critical Reviews in Oncology/Hematology (Both are first author) (doi:10.1016/j.critrevonc.2015.01.002)(Impact factor 5.039) (First & Corresponding author)
  5. Khan, Z.*, Khan A.A.*, Yadav H., Prasad, G.B.K.S., Bisen P.S. (2017) Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma. Cell Mol Biol Lett 22: 8. (doi:10.1186/s11658-017-0038-0) (Impact factor 1.753) (Co-first author)
  6. Khan A.A.*, Khan Z., Malik A., Khan S., Shrivastava A., Jain S.K., Alshamsan A. (2015) Computational prediction of coli proteins host subcellular targeting and their implications in colorectal cancer etiology. Cancer Letters (doi: http://dx.doi.org/10.1016/j.canlet.2015.04.024) (Impact factor 5.016) (First & Corresponding author).
  7. Khan A.A.* (2014) In silico prediction of coli proteins targeting the host cell nucleus, with special reference to their role in colon cancer etiology. J Comp Biol (DOI:10.1089/cmb.2014.0001) (Impact factor 1.67) (Sole author).
  8. *Khan A.A., Cash P. (2013) coli and colon cancer: Is mutY a culprit? Cancer Letters 341(2): 127-131 (Impact factor 4.25) (First & Corresponding author)
  9. *Khan A.A., Khurshid M., Khan S., AlShamsan A. (2013) Gut microbiota and probiotics: Current status and their role in cancer therapeutics. Drug Dev. Res. (DOI 10.1002/ddr.21087) (Impact factor 0.869)[Invited article as subject expert] (First & Corresponding author)
  10. Khan A.A., Khurshid M., Tawfik A.F. (2013) In vitro evaluation of vincristine and fluconazole combination against Candida spp. Pak J Pharm Sci 26(5): 1037-1040 (Impact factor 1.102)
  11. *Khan A.A., Shrivastava A., Khurshid M. (2012) Normal to cancer microbiome transformationand its implication in cancer diagnosis. BBA Rev. Cancer 1826(2): 331-337 (Impact factor 9.886) (First & Corresponding author)
  12. *Khan A.A. and Shrivastava A. (2010) Bacterial infection associated with cancer: Possible implication in etiology with special reference to lateral gene transfer. Cancer Metastasis Rev. 29(2): 331-337 (Impact factor 9.345) (First & Corresponding author)
  13. *Khan A.A. (2010). Intracellular mechanism of Apoptosis. Biol. Sci. 10(4):291-305
  14. *Khan A.A., Jain S.K., Shrivastav A. (2008) Prevalence of dental caries among the population of Gwalior (India) in relation of different associated factors, J. Dent. 2: 81-85 (First & Corresponding author)

As Co-author

  1. Bhat M.A., Al-Omar M.A., Naglah A.M., Khan A.A. (2019) Enaminone derived pyrazoles with antimicrobial activity. Journal of Chemistry (Accepted) (Impact factor: 1.727)
  2. Alhowyan A.A., Altamimi M.A., Kalam M.A., Khan A.A., Badran M., Binkhathlan Z., Alkholief M., Alshamsan A. (2019) Antifungal efficacy of Itraconazole loaded PLGA-nanoparticles stabilized by vitamin-E TPGS: In vitro and ex vivo studies. J Microbiol Methods. pii: S0167-7012(18)30984-9. doi: 10.1016/j.mimet.2019.01.020. [Epub ahead of print]. (Impact factor: 1.7)
  3. Kalam M.A., Khan A.A., Alshamsan A., Haque A., Shakeel F. (2018) Solubility of a poorly soluble immunosuppressant in different pure solvents: Measurement, correlation, thermodynamics and molecular interactions. J Mol Liquids (DOI: 10.1016/j.molliq.2017.11.028) (Impact factor 3.648)
  4. Kalam M.A., Khan A.A., Alshamsan A. (2017) Biodegradable polymeric nanoparticles and vesicular carriers for vaccine delivery via non-invasive routes of administration: A review. Am J Transl Res, 9(1):15-35 (Impact factor 3.146)
  5. Bhat M.A., Khan A.A., Al-Omar M.A., Khan A.A. (2017) Synthesis and anti-Candidal activity of some new pyrazoline derivatives. Biomed Res 28 (7): 3082-3087 (Impact factor 0.226)
  6. Khan A.A., Jabeen M., Alanazi A., Khan A.A. (2016) Antifungal efficacy of amphotericin B encapsulated fibrin microsphere for treating Cryptococcus neoformans infection in Swiss albino mice. Brazilian J Infec Dis (doi: 10.1016/j.bjid.2016.04.006) (Impact factor 1.412)
  7. Malik A., Kumar D., Khan A.A., Khan, A.A., Chaudhary A.A., Husain S.A., Kar P. (2016) Hepatitis B virus precore G1896A mutation in chronic liver disease patients with HBeAg negative serology from North India. Saudi J Biol Sci (doi:10.1016/j.sjbs.2016.05.004) (Impact factor 1.257).
  8. Khan S., Imran A., Khan A.A., Kalam M.A., Alshamsan A. (2016) Systems biology approaches for the prediction of possible role of Chlamydia pneumoniae proteins in the etiology of lung cancer. PLOS One (doi: 10.1371/journal.pone.0148530) (Impact factor 3.234).
  9. Kalam M.A., Khan A.A., Khan S., AlMalik A., Alshamsan A. (2016) Optimizing Indomethacin-loaded Chitosan nanoparticle size, encapsulation, and release using Box-Behnken experimental design. Int J biol macromol 87:329-340 (Impact factor 2.858).
  10. Khan S., Ansari A.A., Khan A.A., Ahmad R. (2016) In vitro evaluation of anticancer and biological activities of synthesized Manganese oxide nanoparticles. Med Chem Comm (doi: 1039/C6MD00219F) (Impact factor 2.319)
  11. Khan, AnsariA.A., Khan A.A.,  Al-Kattan W., Al-Obaid O., Ahmad R. (2016) Design, synthesis and in-vitro evaluation of anticancer and antibacterial potential of surface modified Tb(OH)3@SiO2 core-shell nanoparticles. RSC Advances 6: 18667-18677 (Impact factor 3.84).
  12. Bhat M.A., Khan A.A., Ghabbour H.A., Quah C.K., Fun H.K. (2016) Synthesis, characterization, X-ray structure and antimicrobial activity of N-(4-Chlorophenyl)-2-(pyridin-4-ylcarbonyl) hydrazinecarbothioamide. Trop J Pharm Res 15 (8): 1751-1757 (Impact factor 0.589)
  13. Khan Z., Khan A.A., Prasad G.B.K.S., Khan N., Tiwari R.P., Bisen P.K. (2016) Growth inhibition and chemo-radiosensitization of head and neck squamous cell carcinoma (HNSCC) by Survivin-siRNA Lentivirus. Radiotherapy and Oncology 118(2):359-68 (Impact factor 4.363).
  14. Khurshid M., Akbar R., Nisar M.A., Rahman H., Aslam B., Khan A.A., Rasool M.H. (2015) Bacterial munch for infants: potential pediatric therapeutic interventions of probiotics. Future Microbiology 10(11):1881-95. (Impact factor 4.275)
  15. Khan S., Ansari A.A., Khan A.A., Ahmad R., Al-Obaid O., Al-Kattan W. (2015) In vitro evaluation of anticancer and antibacterial activities of cobalt oxide nanoparticles. J Biol Inorg Chem. 20(8):1319-26. (doi: 10.1007/s00775-015-1310-2) (Impact factor 495)
  16. Muhammad S., Khurshid M., Saleem H.G., Khan A.A. (2015) Characteristic and antibiotic resistance of urinary tract pathogens in Punjab. Jundishapur J Microbiol 8(7): e19272. (doi: 10.5812/jjm.19272v2) (Impact factor 0.78)
  17. Bhat M., Khan A.A., Khan S., Abdl Aziz H.A., Alanazi A.M., Al-Omar M.A. (2014) Synthesis of new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and study of their anti-Candidal and cytotoxic activities. J Chem, Article ID 897141(Impact factor 0.622)
  18. Bhat M., Khan A.A., Khan S., Al-Omar M.A., Parvez M.K., Al Dosari M.S. (2014) Synthesis and anti-Candida activity of N- (4-aryl/cyclohexyl) -2-(pyridine-4-yl carbonyl) hydrazinecarbothioamide. Bioorg Med Chem Letters (DOI:10.1016/j.bmcl.2014.01.060) (Impact factor 2.338)
  19. Farooq F., Rai M., Tiwari A., Khan A.A., Farooq S. (2012) Medicinal potential of Moringa oleifera: An overview of promising healer. Med. Plant. Res. 6 (27): 4368-4374 (Impact factor 0.879)
  20. Shrivastava A., Khan A.A., Shrivastav A., Jain S.K., Singhal P.K. (2012) Kinetic study of purified L-asparaginase from Penicillium Prep. Biotech. Biochem. 42: 574-581 (Impact factor 0.691)
  21. Shrivastava A., Khan A.A., Jain S.K., Singhal P.K., Jain S., Marotta F., Yadav H. (2010) Biotechnological advancement in isolation of anti-neoplastic compounds from natural origin: a novel source of L-asparaginase. Acta Biomedica 81(2):104-108
  22. Bhatnagar P., Khan A.A., Jain M. Kaushik S. & Jain S.K. (2007). Microbiological study of khoa sold in chambal region (Madhya Pradesh): A case study. Indian J. Microbiol. 47(3): 263-266
  23. Bhatnagar P., Khan A.A., Jain M. & Jain S.K. Shrivastav A. (2007). Bacteriological study of khoa sold in Gwalior & Morena city (Madhya Pradesh) in relation to public health. Asian J. Exp. Sci. 21(1): 55-62
  24. Jain M., Khan A.A., Gupta A., Pandey M., Bhatnagar P., Jain S.K. (2008) An epidemic of typhoid fever in a hostel, Indian J. Field Vet. 4(1):46-47
  25. Khan A.A., Shrivastava A. Jain S.K. (2009) In vitro susceptibility of antibiotics against pathogenic bacteria, BIOZONE Int. J. Life Sci. 1(1): 24-27

Magazine Articles

  1. Sharma E., Rochlani D., *Khan A.A. (2011) Automated liver function test: An important advancement in rapid testing of liver function. Medical Equipments and Automation Oct 2011, pp. 55-57
  2. *Khan A.A. (2010) Automated antibacterial susceptibility testing in clinical laboratories. Medical Equipments and Automation May-June 2010: pp. 44-47
  3. Khan A.R., Farooq F., *Khan A.A. (2010) Clinical microbiology laboratory automation: A Way towards improving clinical microbiology diagnosis. Medical Equipments and Automation Nov-Dec 2010: pp. 76-80

Chapters in Books

  1. Jha S., Khan A.A., Ashraf M.T. (2019) Designing of Artificial Metalloenzymes. In: Husain Q., Ullah M. (eds) Biocatalysis. Springer, Cham DOI https://doi.org/10.1007/978-3-030-25023-2_9
  2. Khan A.A., Khan S. (2015) “Probiotics and cancer”. Encyclopedia of Cancer (Ed) Manfred Schwab, Springer
  3. Shrivastava A., Khan A.A., Jain S.K., Singhal P.K. (2012) Bacterial asparaginase: A potential therapeutic agent for leukemia. ”Bacteria and Cancer (Ed) Abdul Arif Khan, Springer Science Publisher, Netherlands
  4. Bhatnagar P, Khan A.A., Jain S.K. and Rai M.K. (2010) "Biodeterioration of archaeological monuments: An approach for restoration". Geomicrobiology (Ed) Sudhir K. Jain, A. Arif Khan, M.K. Rai, Science Publisher, CRC Press, USA
  5. *Khan A.A.*, Bhatnagar P., Jain S.K., Deshmukh S.K., Rai M.K. (2006) “Recent methods for fungal community analysis with special reference to TGGE and DGGE”. Current Advances in Fungal Biotechnology" (Ed.) M. K. Rai Publisher- I. K. International Pvt Ltd. New Delhi, pp. 450-462

Web resources developed for scientific community

  1. Jha S., Ashraf M.T., Khan A.A., Ahmad S. (2016) “Algae Scan” http://www.algaescan.org/index.aspx
  2. Shankar V., Khan A.A. (2009) “Herpes Web” http://herpes.page.tl/

Abstracts Published

  1. Khan A.A. (2014) “E. coli and colon cancer: Who is the culprit?” published in abstract book of 3rd TM World Cancer Conference, USA 
  2. Khan A.A. (2012) “Normal to Cancer Microbiome transformation: Giving clue for cancer detection” published in abstract book of 2nd TM World Cancer Conference, USA 
  3. Khan A.A. (2012) “Bacteriology and Cancer: An old association revisited” published in abstract book of 1st international conference on Biosciences and Bioengineering: A collaborative approach, India
  4. Khan A.A. and Shrivastava A. (2009) “Medical waste disposal system: An integral part of hospital” published in abstract book National seminar on Recent Advances in Environmental Sciences, organized by PG Department of Life Sciences, IASCA, ITM Universe, Gwalior (M.P.)
  5. Khan A.A. (2006) Phylogenetic Analysis of Teeth Decaying Oral Bacteria through CLUSTAL W” published in Abstract book of 4th Annual Rocky Mountain Bioinformatics conference, Colorado USA
  6. Khan A.A., Jain M., Shrivastav A., Jain S.K. (2006) “Bacterial infections jeopardizing patients to cancer” published in Abstract book 47th AMI conference, Bhopal
  7. Bhatnagar P., Mishra A., Khan A.A., Shrivastav A., Jain S.K. (2006) “TGGE & DGGE: An approach for molecular study of microbial community” published in Abstract book 47th AMI conference, Bhopal
  8. Khan A.A. & Shrivastava A. (2004) “Effects of leaf extracts on the growth of E. coli” published in M.P. Science Congress, Indian science congress association, Bhopal chapter